TABLE 3.

Wilcoxon matched-pairs signed-rank test on the region-wise strain and strain rate in the hippocampal subfields and whole hippocampus (A) and non-hippocampal regions (B) (N = 6). Percentages in strain difference and strain rate difference between the TH-Model and NTH-model were calculated across all simulations and presented in the form of median and two quartile values with Q1 as 25th percentile value and Q3 as 75th percentile value. Note that N equals to the number of impacts simulated by each model. CA: cornu ammonis; DG: dentate gyrus; HP Tail: hippocampal tail; Ventral DC: ventral diencephalon; CC: corpus callosum.

A	Regions	Percentage in strain difference [median (Q1, Q3)] (%)		p	Percentage in strain rate difference [median (Q1, Q3)] (%)		p
	CA1	44.6	(33.6, 53.0)	0.028	92.3	(69.3, 98.5)	0.028
	CA2/3	64.6	(62.7, 104.3)	0.028	97.9	(81.0, 121.0)	0.028
	CA4/DG	11.7	(3.2, 21.8)	0.046	23.7	(17.2, 67.6)	0.028
	HP Tail	33.9	(18.6, 54.3)	0.046	35.5	(12.5, 67.6)	0.046
	Subiculum	6.9	(5.5, 11.2)	0.046	65.3	(61.6, 89.7)	0.028
	Presubiculum	19.9	(11.6, 28.0)	0.028	2.7	(1.9, 3.7)	0.046
	Hippocampus	29.5	(25.3, 33.2)	0.028	57.5	(34.7, 91.9)	0.028
B	Regions	Percentage in strain difference [median (Q1, Q3)] (%)		p	Percentage in strain rate difference [median (Q1, Q3)] (%)		p
	Amygdala	33.8	(17.1, 39.3)	0.028	50.9	(40.4, 56.1)	0.028
	Ventral DC	8.2	(4.6, 12.2)	0.028	9.35	(3.7, 13.1)	0.028
	Pallidum	−1.7	(−4.2, 2.1)	0.249	−0.6	(−4.2, 4.4)	0.753
	Putamen	−1.4	(−2.3, 2.8)	0.249	2.2	(−0.4, 4.7)	0.173
	Caudate	1.5	(0.7, 5.5)	0.917	0.1	(−2.5, 0.9)	0.463
	CC	0.7	(0.0, 1.3)	0.249	2.5	(−0.4, 3.6)	0.116