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. 2022 Mar 22;13:848709. doi: 10.3389/fpsyt.2022.848709

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Copyright © 2022 Ye, Ji, Wang, Wang, Li, Chen, Cheng, Li and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Correlation between value of lrFCD in right medial frontal gyrus and HAMD scores after SD, n = 21. (B) Correlation between value of lrFCD in right medial frontal gyrus and concentration of 5-HT after SD, n = 17. (C) Correlation between value of lrFCD in right medial frontal gyrus and concentration of NE after SD, n = 17. FCD, functional connectivity density; HAMD, Hamilton Depression Rating Scale; SD, sleep deprivation; 5-HT, serotonin; NE, norepinephrine.