TABLE 4.
Coronary atherosclerosis burden of lesions in “gray zone.”
| FFR ≤ 0.75 vs. FFR 0.76–0.8 |
FFR 0.76–0.8 vs. FFR > 0.8 |
|||||
| FFR ≤ 0.75 | FFR 0.76–0.8 | P Value* | FFR 0.76–0.8 | FFR > 0.8 | P Value† | |
| Total plaque burden of target vessel (%) | 34.6 (30.8, 39.0) | 33.2 (29.1, 38.6) | 0.381 | 33.2 (29.1, 38.6) | 30.2 (26.4, 36.5) | 0.003 |
| Non-calcified plaque volume of target vessel (mm3) | 60.5 (26.4, 114.8) | 58.4 (26.1, 111.1) | 1.000 | 58.4 (26.1, 111.1) | 34.3 (15.2, 71.0) | 0.024 |
| Lesion length (mm) | 22.3 (14.0, 34.9) | 21.3 (15.6, 33.6) | 1.000 | 21.3 (15.6, 33.6) | 17.6 (11.0, 26.0) | 0.012 |
| Plaque volume of target lesion (mm3) | 153 (65.2, 254.8) | 159.5 (113.3,241.2) | 1.000 | 159.5 (113.3,241.2) | 87 (39.3, 180.9) | 0.000 |
| Non-calcified plaque volume of target lesion (mm3) | 20.9 (9.2, 44.7) | 18.2 (9.6,42.3) | 1.000 | 18.2 (9.6,42.3) | 12.5 (4.6, 26.9) | 0.007 |
| Calcified plaque volume of target lesion (mm3) | 11.7 (0.72, 52.8) | 21.6 (3.4,72.7) | 0.290 | 21.6 (3.4,72.7) | 7.6 (0.1, 29.9) | 0.008 |
| Lumen area of target lesion (mm2) | 1.81 (1.17, 2.38) | 2.3 (1.65,3.05) | 0.012 | 2.3 (1.65,3.05) | 2.5 (1.86, 3.12) | 0.500 |
| Lumen diameter of target lesion (mm) | 1.52 (1.22, 1.74) | 1.71 (1.46,1.97) | 0.011 | 1.71 (1.46,1.97) | 1.78 (1.54, 2) | 0.516 |
Data are median, interquartile range are in parentheses.
*Comparison of coronary plaque burden between lesions with FFR ≤ 0.75 and 0.76–0.8. †Comparison of coronary plaque burden between lesions with FFR > 0.8 and 0.76–0.8. FFR, fractional flow reserve.