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. 2022 Mar 22;9:819460. doi: 10.3389/fcvm.2022.819460

TABLE 6.

Univariate logistic regression analysis of the effects of CTA characteristics on FP and FN lesions by CT-FFR in different FFR level.

FFR < 0.76
0.76 ≤ FFR ≤ 0.8
FFR > 0.8
OR p Value OR p Value OR p Value
LAD 2.059 (0.374–11.336) 0.407 0.722 (0.262–1.986) 0.528 0.839 (0.501–1.406) 0.505
ICA > 50% 1.021 (0.985–1.021) 0.985 1.582 (0.439–5.705) 0.483 2.684 (1.099–6.553) 0.030
CACS of target lesion 1.001 (0.996–1.006) 0.605 1.009 (1.000–1.018) 0.044 1.000 (0.998–1.002) 0.907
Plaque burden of target lesion 1.001 (0.994–1.008) 0.848 1.023 (0.960–1.091) 0.483 1.027 (0.993–1.062) 0.117
Calcified volume of target lesion 1.021 (0.989–1.054) 1.021 1.016 (0.997–1.035) 0.103 1.000 (0.995–1.006) 0.957
Lumen area of target lesion 0.627 (0.383–1.028) 0.064 0.689 (0.416–1.140) 0.147 0.567 (0.3510.915) 0.020
Lumen diameter of target lesion 0.274 (0.06–1.247) 0.094 0.238 (0.047–1.197) 0.082 0.296 (0.098–0.887) 0.030

Data are median, 95% CI confidence interval are in parentheses.

CACS, coronary artery calcium score; FN, false negative; FP, false positive; FFR, fractional flow reserve; CT-FFR, fractional flow reserve derived from computed tomography; CTA, computed tomography angiography; ICA, invasive coronary angiography; LAD, left anterior descending artery.