TABLE 6.
Univariate logistic regression analysis of the effects of CTA characteristics on FP and FN lesions by CT-FFR in different FFR level.
| FFR < 0.76 |
0.76 ≤ FFR ≤ 0.8 |
FFR > 0.8 |
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| OR | p Value | OR | p Value | OR | p Value | |
| LAD | 2.059 (0.374–11.336) | 0.407 | 0.722 (0.262–1.986) | 0.528 | 0.839 (0.501–1.406) | 0.505 |
| ICA > 50% | 1.021 (0.985–1.021) | 0.985 | 1.582 (0.439–5.705) | 0.483 | 2.684 (1.099–6.553) | 0.030 |
| CACS of target lesion | 1.001 (0.996–1.006) | 0.605 | 1.009 (1.000–1.018) | 0.044 | 1.000 (0.998–1.002) | 0.907 |
| Plaque burden of target lesion | 1.001 (0.994–1.008) | 0.848 | 1.023 (0.960–1.091) | 0.483 | 1.027 (0.993–1.062) | 0.117 |
| Calcified volume of target lesion | 1.021 (0.989–1.054) | 1.021 | 1.016 (0.997–1.035) | 0.103 | 1.000 (0.995–1.006) | 0.957 |
| Lumen area of target lesion | 0.627 (0.383–1.028) | 0.064 | 0.689 (0.416–1.140) | 0.147 | 0.567 (0.3510.915) | 0.020 |
| Lumen diameter of target lesion | 0.274 (0.06–1.247) | 0.094 | 0.238 (0.047–1.197) | 0.082 | 0.296 (0.098–0.887) | 0.030 |
Data are median, 95% CI confidence interval are in parentheses.
CACS, coronary artery calcium score; FN, false negative; FP, false positive; FFR, fractional flow reserve; CT-FFR, fractional flow reserve derived from computed tomography; CTA, computed tomography angiography; ICA, invasive coronary angiography; LAD, left anterior descending artery.