Table 1.

Summary of statistical analyses of clinical scores.

Comparison	Incidence ratea (Risk of disease)	Global prevalenceb/incidence	Onsetc	Severityd
CS Low vs. sham	1.241	3.003	Day 19 vs. 15	1.232***
CS Med vs. sham	1.015	1.333	Day 19 vs. 18	1.248***
CS High vs. sham	0.605	0.500	Day 19 vs. 25	0.991
CS Low vs. CS Med	1.222	2.250	Day 15 vs. 18	0.987
CS Low vs. CS High	2.051*	6.000	Day 15 vs. 25*	1.244***
CS Med vs. CS High	1.678	2.667	Day 18 vs. 25	1.259***

Remarks:

Statistical significance: *p ≤ 0.05, **p ≤ 0.01, and ***p ≤ 0.001.

^aNumber of cases over total number of mice per day; an incidence rate ratio lower than 1 is interpreted as showing lower incidence in the first group than in the second group, and the converse is true for values higher than 1.

^bNumber of mice that show the effect of the disease at least once throughout the study.

^cTime at which the mice show an effect of the disease for the first time as analyzed by using non-parametric Kaplan-Meier estimator and log-rank tests.

^dDegree of disease symptoms (expressed as clinical scores) over time; a value smaller than 1 indicates that the clinical score in the first group is lower than that in second group, and the converse is true for values higher than 1.