FIGURE 4.

DKI and WT mice display similar changes in liver and skeletal muscle glycogen following a maximal running test at a 5° incline. Glycogen content was assessed in (A) liver and (C) skeletal muscle from rested mice and maximally exercised mice. Change in glycogen (Δglycogen content) in (B) liver and (D) skeletal muscle was determined by the difference between individual glycogen content of maximally exercised mice and the average glycogen content of rested mice from the same genotype. Male mice, 17–20 weeks, n = 7–10. **p < 0.01, ***p < 0.001, ****p < 0.0001.