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. 2022 Mar 24;8(4):e09184. doi: 10.1016/j.heliyon.2022.e09184

Table 3.

Genetic model association analysis with AA susceptibility (data shown for MASP2 and C11orf30 only).

Gene SNP Model Genotype Controls (n, %) Patients (n, %) OR (95% CI) P-value
MASP2 rs2273346 Codominant A/A 126 (85.1%) 143 (94.1%) 1.00 0.0026
A/G 22 (14.9%) 7 (4.6%) 0.28 (0.12–0.68)
G/G 0 (0%) 2 (1.3%) NA (0.00-NA)
Dominant A/A 126 (85.1%) 143 (94.1%) 1.00 0.0099
A/G-G/G 22 (14.9%) 9 (5.9%) 0.36 (0.16–0.81)
Recessive A/A-A/G 148 (100%) 150 (98.7%) 1.00 0.098
G/G 0 (0%) 2 (1.3%) NA (0.00-NA)
C11orf30 rs2155219 Codominant T/T 43 (29.9%) 31 (20.5%) 1.00 0.0069
G/T 79 (54.9%) 75 (49.7%) 1.32 (0.75–2.30)
G/G 22 (15.3%) 45 (29.8%) 2.84 (1.43–5.64)
Dominant T/T 43 (29.9%) 31 (20.5%) 1.00 0.064
G/T-G/G 101 (70.1%) 120 (79.5%) 1.65 (0.97–2.81)
Recessive T/T-G/T 122 (84.7%) 106 (70.2%) 1.00 0.0027
G/G 22 (15.3%) 45 (29.8%) 2.35 (1.33–4.17)