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. 2022 Mar 1;26(7):1969–1978. doi: 10.1111/jcmm.17221

FIGURE 2.

FIGURE 2

Knockdown of CD44 induces apoptosis and promotes cell‐cycle arrest at the G1/G0 phase of HCT116‐CSCs. (A) flow cytometric analysis detects apoptosis of HCT116‐CSCs transfected with CD44‐siRNA and si‐NC; (B) greater apoptotic rates of HCT116‐CSCs transfected with CD44‐siRNA are detected as compared to si‐NC; (C) flow cytometric analysis detects the number of HCT116‐CSCs transfected with CD44‐siRNA and si‐NC at G0/G1, S and G2/M phases; (D) flow cytometry detects higher proportions of HCT116‐CSCs transfected with CD44‐siRNA relative to si‐NC at the G0/G1 phase and lower proportions of HCT116‐CSCs transfected with CD44‐siRNA relative to si‐NC at the S phase. *p < 0.05