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. 2022 Feb 2;12(7):4358–4369. doi: 10.1039/d1ra07984k

Comparison of the current catalyst with reported catalysts for the synthesis of 1,2,4,5-tetrasubstituted imidazole derivativesa.

Entry Catalyst Solvent Temp. (°C) Time (min) Yieldb (%) References
1 BF3·SiO2 Solvent-free 140 120 92 50
2 SiO2·NaHSO4 Solvent-free 140 120 92 51
3 TiCl4·SiO2 Solvent-free 110 190 75 52
4 PEG-400 Solvent-free 110 360 86 53
5 Glycerol Solvent-free 90 180 96 54
6 l-Proline in MeOH 60 540 78 10
7 Fe3O4–PEG–Cu Solvent-free 110 55 96 55
8 InCl3·3H2O MeOH 25 498 82 56
9 DABCO t-BuOH 60 800 92 13
10 K5CoW12O40·3H2O Solvent free 140 160 95 16
11 [(CH2)4SO3HMIM][HSO4] Solvent free 140 120 94 57
12 ZSM-11 zeolite Solvent-free 110 30 95 Present
a

Reaction conditions: benzil (1.0 mmol), aldehyde (1.0 mmol), aniline (1.0 mmol), NH4OAc (3.0 mmol), ZSM-11 zeolite catalyst of time 48 h (0.05 g).

b

Isolated yield.