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. 2022 Mar 22;13:830439. doi: 10.3389/fphar.2022.830439

TABLE 3.

Metabolic pathway enrichment table of rat serum.

NO. Pathway Name Total cmpd Hits RawP -log(p) Impact Details
1 Biosynthesis of unsaturated fatty acids 36 5 4.0831E-6 5.389 0.0 KEGG
2 Butanoate metabolism 15 2 0.0057498 2.2403 0.0 KEGG
3 Synthesis and degradation of ketone bodies 5 1 0.039185 1.4069 0.0 KEGG
4 Linoleic acid metabolism 5 1 0.039185 1.4069 1.0 KEGG
5 valine, leucine and isoleucine biosynthesis 8 1 0.062015 1.2075 0 KEGG
6 Ascorbate and aldarate metabolism 10 1 0.076958 1.1137 0.25 KEGG
7 Pentose and glucuronate interconversions 18 1 0.13457 0.87104 0.125 KEGG
8 Citrate cycle_(TCA cycle) 20 1 0.14845 0.82841 0.03273 KEGG
9 Propanoate metabolism 23 1 0.16889 0.7724 0.0 KEGG
10 Alanine, aspartate and glutamate metabolism 28 1 0.20195 0.69475 0.0 KEGG
11 Inositol phosphate metabolism 30 1 0.21484 0.66789 0.0 KEGG
12 Arachidonic acid metabolism 36 1 0.25235 0.59799 0.33292 KEGG
13 Fatty acid metabolism 39 1 0.27049 0.56785 0.0 KEGG
14 Fatty acid elongation 39 1 0.27049 0.56785 0.0 KEGG
15 valine, leucine and isoleucine degradation 40 1 0.27645 0.55839 0.0 KEGG
16 Fatty acid biosynthesis 47 1 0.3169 0.49908 0.01472 KEGG
17 Aminoacyl-tRNA biosynthesis 48 1 0.32251 0.49146 0.0 KEGG

Total Compound: the total number of compounds in the pathway; hits: the matched number from the user uploaded data; RawP: the original p-value calculated from the enrichment analysis; Impact: pathway impact value calculated from pathway topology analysis.