Table 1.

Schedule of study enrolment, interventions, and assessments

Time point	Study period
	Enrolment	Allocation	Treatment	Discharge	Post-allocation												Close-out
	Outpatient clinic /Admission	Before Surgery	Surgery	After Surgery	Month 1 (T1)	Month 3 (T2)	Month 6 (T3)	Month 9 (T4)	Month 12 (T5)	Month 18 (T6)	Month 24 (T7)	Month 30 (T8)	Month 36 (T9)	Month 42 (T10)	Month 48 (T11)	Month 54 (T12)	Month 60 (T13)
Enrolment
Eligibility screen	×
Informed consent	×
Allocation		×
Interventions
LPD			×
OPD			×
Assessments
Baseline characteristics	×
Blood routine	×			×		×	×	×	×	×	×	×	×	×	×	×	×
Blood biochemistry	×			×		×	×	×	×	×	×	×	×	×	×	×	×
Tumour marker	×			×		×	×	×	×	×	×	×	×	×	×	×	×
Abdominal CT scan	×			×		×	×	×	×	×	×	×	×	×	×	×	×
Surgical record			×
Postoperative record				×
Pathological findings				×
Adjuvant therapy					×	×	×	×	×	×	×	×	×	×	×	×	×
Survival status						×	×	×	×	×	×	×	×	×	×	×	×

LPD, laparoscopic pancreaticoduodenectomy; OPD, open pancreaticoduodenectomy.