Table 3.

Themes and supporting paraphrased quotes from interviews about HPV vaccination with 16 primary care patients taking PrEP

Domain	Theme	Supporting quotes
Attitudes	There is a commitment to preventative health	‘Anything that prevents cancer is a good thing.’ − 56 years old, unvaccinated ‘All vaccines are extremely important.’ − 27 years old, vaccinated ‘[There is] peace of mind that you are protecting yourself to the extent you can.’ − 43 years old, unsure of vaccination status ‘Sex is universal, everyone is having sex. To be safe everyone should get it.’ − 23 years old, vaccinated ‘I like knowing it is another safeguard/layer of protection, similar to PrEP as a level of protection… It is another way to protect myself.’ – 29 years old, unvaccinated (with appointment scheduled to get vaccinated)
Beliefs	There are gaps in knowledge about HPV risks and immunisation options	‘I don't really know anything. I think the effects are worse in females than males.’ − 30 years old, vaccinated ‘You can get genital warts. It can be very deadly for women if they get it.’– 26 years old, unvaccinated ‘It causes warts also known as crabs.’ − 23 years old, vaccinated ‘Males are generally asymptomatic, though if they have it, they can spread to women who can have cervical cancer. I don't really know.’ – 30 years old, vaccinated ‘It is something that is mainly an issue for girls, but I don't know much about the virus specifically or what it does.’ – 29 years old, vaccinated
Barriers	The largest potential barriers are age/lack of knowledge around new age guidelines, lack of doctor recommendation, and lack of insurance coverage	‘[The only barrier would be] my doctor not recommending it.’ – 51 years old, unsure of vaccinated status ‘[The only barrier would be] age. I did not know you could get it now, last I heard vaccine cut off was 26.’– 29 years old, vaccinated ‘[The only barrier would be] if I didn't have any insurance or ability to pay for it.’ – 23 years old, vaccinated ‘I happen to be outside the age bracket, so it wouldn't apply specifically to me.’ – 55 years old, unvaccinated ‘I didn’t even know I could get it. I thought I was too old now.’ – 29 years old, unvaccinated, (with appointment scheduled to get vaccinated)

HPV, human papillomavirus; PrEP, pre-exposure prophylaxis.