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. 2022 Apr 3;10(2):e002639. doi: 10.1136/bmjdrc-2021-002639

Table 2.

Glucose, insulin and C-peptide concentrations during the OGTT


Malaria negative Peripheral malaria Peripheral+placental malaria P value P value adjusted
N 13–16 36–43 11–14
Fasting glucose (mmol/L) 4.5±0.6 4.5±0.6 5.8±0.7 0.21 0.29
Glucose 30 min (mmol/L) 6.7±1.2 6.6±1.0 7.9±1.5 0.002 0.01
Glucose 120 min (mmol/L) 6.6 (5.9–6.9) 6.1 (5.2-6-8) 6.6 (5.4–7.3) 0.35 0.33
Fasting insulin (pmol/L)∞ 40 (22–57) 53 (35–65) 64 (30–70) 0.11 0.13
Insulin 30 min (pmol/L)∞ 318 (174–539) 252 (101–414) 287 (218–389) 0.92 0.67
Insulin 120 min (pmol/L)∞ 274 (197–337) 252 (165–451) 206 (106–333) 0.15 0.12
Fasting C-peptide (pmol/L)∞ 424 (397–567) 443 (374–526) 362 (280–670) 0.76 0.96
C-peptide 30 min (pmol/L)∞ 1562 (1018–1906) 1295 (964–1897) 1324 (1170–1569) 0.97 0.97
C-peptide 120 min (pmol/L)∞ 1622 (1360–1081) 1666 (1293–2296) 1586 (1167–1975) 0.70 0.62
HOMA-IR∞ 1.13 (0.62–1.81) 1.61 (1.10–1.92) 1.88 (0.88–2.15) 0.18 0.21

∞P values from log-transformed data due to skewed residuals.

HOMA-IR, Homeostatic Model Assessment for Insulin Resistance; OGTT, oral glucose tolerance test.