Table 3.

Virologic HIV-1 characteristics by period of donation

Characteristics	REDS-II (2007 – 2011)		REDS-III (2012 – 2017)		Total	p-value**
	n (%)	95% CI	n (%)	95% CI	n
Genotypes
B	229 (75.3)	(70.5 – 80.2)	140 (70.0)	(63.6 – 76.4)	369	0.13
Non-B	63 (20.7)	(16.2 – 25.3)	44 (22.0)	(16.3 – 27.7)	107
A	1 (0.3)	(0.0 – 1.0)	-	-
C	14 (4.6)	(2.3 – 7.0)	8 (4.0)	(1.3 – 6.7)
D	1 (0.3)	(0.0 – 1.0)	4 (2.0)	(0.06 – 3.9)
F/F1	47 (15.5)	(11.4 – 19.5)	30 (15.0)	(10.0 – 19.9)
G	-	-	2 (1.0)	(0 – 2.4)
Recombinants	12 (4.0)	(1.8 – 6.1)	16 (8.0)	(4.2 – 11.8)	28
Resistance
To NRTI*	15 (4.9)	-	11(5.5)	-	26	0.8
To NNRTI †	23 (7.6)	-	16 (8.0)	-	39	0.8
To PI ‡	18 (5.9)	-	6 (3.0)	-	24	0.1
Any antiretroviral mutation
SDRMs §	37	12.2%	27	13.5%	64	0.6

^*Nucleoside Reverse Transcriptase Inhibitor

^†Non-Nucleoside Reverse Transcriptase Inhibitor

^‡Protease Inhibitors

^§Surveillance Drug Resistance Mutations

^**p-value for genotype B, non-B, recombinant by REDS-II/III