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. 2022 Feb 9;9(10):2105152. doi: 10.1002/advs.202105152

Figure 2.

Figure 2

Degradable gelatin‐based IPN cryogel hemostat for rapidly stopping deep noncompressible hemorrhage and improving wound healing. A) Schematic representation of GT/DA cryogel formation and different fixed shapes of GT25/DA0 and GT25/DA8. B) Microtopography observation of GT25/DA8 in free shape, fixed shape, and recovered shape. Scale bar = 200 µm. C) In vivo hemostatic performance of cryogel in rabbit liver defect hemorrhage model. D) Wound contraction rate of in vivo wound‐healing evaluation. Reproduced with permission.[ 35 ] Copyright 2020, American Chemical Society. DA, dopamine; EDC, 1‐(3‐dimethylaminopropyl)‐3‐ethylcarbodii‐mide hydrochloride; GT, gelatin; IPN, interpenetrating polymer network; NHS, N‐hydroxysuccinimide; SP, sodium periodate.