The model simulated for the release profiles of SA-SLNs-SE and SA-SLNs-DE.

Model	SA-SLNs-SE		SA-SLNs-DE
	Equation	r	Equation	r
Zero order	R = 3.5922t + 13.611	0.8527	R = 4.0223t + 16.205	0.8514
First order	ln(100 − R) = −0.102t + 4.4462	0.8950	ln(100 − R) = −0.0723t + 4.4609	0.9083
Higuchi	R = 20.161t1/2 – 5.4687	0.9427	R = 22.655t1/2 – 5.3249	0.9446
Ritger–Peppas	ln R = 1.1084 ln t + 1.5359	0.9045	ln R = 1.0734 ln t + 1.7394	0.8823
Hixon–Crowell	(100 − R)1/3 = −0.087t + 4.4186	0.8818	(100 − R)1/3 = −0.1116t + 4.381	0.8916