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. 2022 Mar 22;12:861489. doi: 10.3389/fcimb.2022.861489

Table 1.

Updated total Neisseria Ng-MIP and Nm-MIP allelic information and sequence diversity.

MIP protein Characteristic Year
Accessed 2015 Accessed 2022
Ng-MIP Number of gonococcal genomes 1217 12805
Gene presence 1217/1217 12805/12805
Number of allelic loci 25 66
Non-redundant Ng-MIP amino acid sequences 16 32
Majority Alleles 10 (49% of isolates)
35 (35% of isolates)
10 (64% of isolates)
35 (22% of isolates)
Nm-MIP Number of meningococcal isolates 4643 26941
Gene presence 4643/4643 (present across 15 sequence types) 26940/26941*
Number of allelic loci 91 356 with isolates (additional 387 with no isolates)
Non-redundant Nm-MIP amino acid sequences 44 149
Majority Alleles 2 (49% of isolates; Type I Nm-MIP)
1 (29% of isolates; Type II Nm-MIP)
7 (10% of isolates; Type IV Nm-MIP)
2 (44% of isolates)
1 (28% of isolates)
7 (10% of isolates)

*Gene is absent in id 51598 ( Supplementary Table 1 ).