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. 2022 Apr 4;12:42. doi: 10.1186/s13578-022-00776-9

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 12 — Upregulation of UBIAD1 mitigated Golgi apparatus stress associated with OGD/R-induced ferroptosis in vitro. A–D and H–K Protein expression of GM130, SPCA1, and GOLPH3 in various experimental groups as determined by western blotting. E and L Levels of CoQ10 production in various experimental groups as assayed using CoQ10 assay kit. F and M The mRNA expression of eNOS in neurons as detected using PCR assay. G and N Levels of NO in various experimental groups as assayed using NO assay kit. n = 3, all data are expressed as the mean ± SD, *P < 0.05, **P < 0.01; CTR + vector-UBIAD-OE group vs. OGD/R + vector-UBIAD-OE group and OGD/R + vector-UBIAD-OE group vs. OGD/R + UBIAD-OE group; CTR + vector-UBIAD-siRNA group vs. OGD/R + vector-UBIAD-siRNA group and OGD/R + vector-UBIAD-siRNA group vs. OGD/R + UBIAD-siRNA group