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. 2022 Mar 22;12:853336. doi: 10.3389/fonc.2022.853336

Table 2.

The differences of clinicoradiological characteristics in between training and testing datasets.

Group taining testing P-value
N 402 99
Age (years) 51.66 ± 10.89 52.93 ± 11.03 0.301
PLT, 10^9/L 156.62 ± 77.43 143.45 ± 62.58 0.117
ALT, IU/L 59.16 ± 87.60 85.86 ± 119.67 0.012
AST, IU/L 55.04 ± 73.86 80.45 ± 107.22 0.006
ALB, g/L 41.96 ± 5.11 41.48 ± 6.26 0.422
TBIL, μmol 17.42 ± 8.33 21.64 ± 32.26 0.020
ALP, IU/L 112.84 ± 91.99 112.46 ± 41.64 0.969
APTT, sec 27.61 ± 14.69 24.60 ± 10.11 0.054
PT, sec 13.17 ± 10.65 11.75 ± 1.17 0.186
INR 1.00 ± 0.09 1.04 ± 0.14 <0.001
Gender 0.146
0, male 348 (86.57%) 80 (80.81%)
1, female 54 (13.43%) 19 (19.19%)
AFP 0.761
0, normal 153 (38.93%) 39 (40.62%)
1, abnormal 240 (61.07%) 57 (59.38%)
Hbs Ag 0.912
0, Hbs Ag(-) 51 (12.85%) 13 (13.27%)
1, Hbs Ag(+) 346 (87.15%) 85 (86.73%)
Child-Pugh 0.414
0, A 394 (98.25%) 96 (96.97%)
1, B 7 (1.75%) 3 (3.03%)
Cirrhosis 0.611
0, no 107 (26.75%) 29 (29.29%)
1,yes 293 (73.25%) 70 (70.71%)
No. of nodes 0.254
0, 1 373 (92.79%) 95 (95.96%)
1, ≥ 2 29 (7.21%) 4 (4.04%)
The maximum length 0.739
0,≤5cm 275 (68.41%) 66 (66.67%)
1, >5cm 127 (31.59%) 33 (33.33%)
Shape 0.179
0, circle 161 (40.05%) 47 (47.47%)
1, irregular 241 (59.95%) 52 (52.53%)
Satellite nodules 0.048
0, absent 365 (91.02%) 96 (96.97%)
1, present 36 (8.98%) 3 (3.03%)
Capsule 0.496
0, absence or incomplete 194 (48.26%) 44 (44.44%)
1, complete 208 (51.74%) 55 (55.56%)
Intratumoral hemorrhage 0.137
0, absent 252 (62.69%) 54 (54.55%)
1, present 150 (37.31%) 45 (45.45%)
Intratumoral fat 0.796
0, absent 341 (84.83%) 85 (85.86%)
1, present 61 (15.17%) 14 (14.14%)
Arterial peritumoral enhancement 0.294
0, absent 301 (74.88%) 69 (69.70%)
1, present 101 (25.12%) 30 (30.30%)
Peritumoral hypotensity on HBP 0.034
0, absent 313 (77.86%) 67 (67.68%)
1, present 89 (22.14%) 32 (32.32%)
MVI grade 0.993
0 202 (50.25%) 50 (50.51%)
1 166 (41.29%) 41 (41.41%)
2 34 (8.46%) 8 (8.08%)

MVI, microvascular invasion; M0: no MVI detected; M1 (low-risk group): 0<the number of MVI ≤ 5 and MVI occurred in the proximal paracancerous liver; M2 (high-risk group): the number of MVI > 5 MVI or MVI occurred in the distal paracancerous liver tissue area (> 1 cm). PLT, platelet count; ALT, alanine transarninase; AST, aspertate aminotransferase; ALB, serum albumin; TBIL, serum total bilirubin; ALP, alkaline phosphatase; APTT, activated partial thromboplastin time; PT, prothrombin time; INR, international normalized ratio; AFP, serum afetoprotein; Hbs Ag, hepatitis B surface antigen; HBP, hepatobiliary phase