TABLE 1.

In vitro activity of macrolide antibiotics for S. oralis and S. mitis

Organism	Antibiotic	MIC (μg/ml)a
		Range	50%	90%
S. oralis	Erythromycin	0.016–>512	0.125	8
	Clarithromycin	0.016–2048	0.031	8
	Roxithromycin	≤0.016–>512	0.25	8
	Azithromycin	≤0.016–>512	0.5	16
	Rokitamycin	0.031–4	0.125	0.5
S. mitis	Erythromycin	0.016–>512	0.125	32
	Clarithromycin	0.016–>512	0.031	32
	Roxithromycin	≤0.016–2048	0.125	64
	Azithromycin	≤0.016–2048	0.5	64
	Rokitamycin	0.031–8	0.125	1

^a50% and 90%, MIC₅₀ and MIC₉₀, respectively.