Table 1.
Demographic and clinical parameters (plus available cortisol data)
| Variables | FEMD | RMD | Controls | Test | Test value | p-value | p-FEMD/C | p-RMD/C | p-RMD/FEMD |
|---|---|---|---|---|---|---|---|---|---|
| Age (years) | 33.5 (25.0;46.3;82) | 42.0 (30.0;52.0;47) | 38.0 (28.0;47.5;129) | H-test | KW = 5.15 | 0.076 | 0.214 | 0.214 | 0.082 |
| Disease duration (years) | 0 (0;0;82) | 4.5 (2.0;9.8;32) | – | U-test | W = 82.0 | < 0.001 | |||
| Gender (female/male) | 43/39 | 33/14 | 77/52 | Chi-Square | χ2 = 3.93 | 0.140 | 0.371 | 0.371 | 0.221 |
| BMI_T0 | 23.1 (20.3;25.6;82) | 25.0 (21.4;27.6;47) | 24.1 (21.8;27.2;129) | H-test | KW = 6.40 | 0.041 | 0.054 | 0.431 | 0.054 |
| BMI_T6 | 24.0 (21.3;27.3;63) | 24.8 (22.3;27.8;36) | – | U-test | W = 997.5 | 0.323 | |||
| Test value | W = 494 | W = 149 | |||||||
| T0–T6 p-value | 0.008 | 0.088 | |||||||
| Smoking status (yes/no) | 42/40 | 22/24 | 29/100 | Chi-Square | χ2 = 21.22 | < 0.001 | < 0.001 | 0.003 | 0.854 |
| Cigarettes/day-T0 | 4.5 (0;20.0;82) | 0 (0;15;46) | 0 (0;0;129) | H-test | KW = 29.61 | < 0.001 | < 0.001 | < 0.001 | 0.337 |
| Cigarettes/day-T6 | 0 (0;15.0;63) | 0 (0;14.3;36) | – | U-test | W = 1219.0 | 0.506 | |||
| Test value | W = 109 | W = 36.5 | |||||||
| T0–T6 p-value | 0.129 | 0.788 | |||||||
| AMI-T6 (g) | 4.10 (2.81;5.69;54) | 3.60 (2.69;6.44;31) | – | U-test | W = 801.0 | 0.853 | |||
| HAMD-21-T0 | 19.0 (14.8;23.0;82) | 22.0 (15.0;29.0;47) | – | U-test | W = 1637.0 | 0.156 | |||
| HAMD-21-T6 | 6.0 (3.0;10.0;63) | 8.0 (6.0;13.0;37) | – | U-test | W = 760.5 | 0.004 | |||
| Test value | W = 1759 | W = 660 | |||||||
| T0–T6 p-value | < 0.001 | < 0.001 | |||||||
| GAF-T0 | 50.0 (48.5;60.0;80) | 50.0 (41.0;60.0;47) | – | U-test | W = 2042.0 | 0.415 | |||
| GAF-T6 | 70.0 (65.8;80.8;60) | 65.0 (60.0;76.5;37) | – | U-test | W = 1398.0 | 0.032 | |||
| Test value | W = 76.5 | W = 35 | |||||||
| T0–T6 p-value | < 0.001 | < 0.001 | |||||||
| Cortisol-T0 (ng/mL) | 330 (181;713;37) | 343 (166;1130;20) | 229 (171;853;46) | H-test | KW = 0.665 | 0.717 | 0.823 | 0.823 | 0.874 |
| Cortisol-T6 (ng/mL) | 212 (140;532;27) | 218 (145;818;13) | – | U-test | W = 149.5 | 0.461 | |||
| Test value | W = 318 | W = 55 | |||||||
| T0–T6 p-value | 0.001 | 0.542 |
Data are presented as median (quartile 1; quartile 3; sample size) or number of cases
AMI cumulative amitriptyline dosage, HAMD 21-item Hamilton Scale for Depression, GAF Global Assessment of Functioning
Significant p-values are highlighted in bold font