TABLE 1.

MICs of antibiotics for K. pneumoniae isolates and comparators and for E. coli J62-1 and its transconjugant with the SHV-13 β-lactamase^a

Isolate	Gm	Ak	Cip	Azt	Caz	Caz-Clav	Ctx	Ctr	Cxm	Fox	Pip	Pip-Taz	Imp	Profile of plasmid sizes (kb)
801	0.5	2	0.06	1	8	0.25	4	8	16	4	512	4	0.25	170/50/3.1
802	0.5	2	0.25	2	16	0.5	4	16	16	8	1,024	16	0.25	170/100/50/3.5
803	1	2	0.03	256	256	0.5	8	16	16	4	512	8	0.25	170/50/3.1
804	0.25	1	0.03	0.5	16	0.25	4	16	16	2	1,024	4	0.25	170/50/3.1
805	0.5	2	0.03	1	8	0.25	4	32	8	4	512	8	0.25	170/50/3.1
806	1	4	0.06	8	32	0.5	4	32	16	4	1,024	8	0.5	170/50/3.1
810	0.25	4	0.03	1	4	0.25	2	16	16	4	512	4	0.12	170/50/3.1
812	0.25	2	0.03	1	4	0.25	4	8	8	4	512	2	0.25	170/50/3.1
820	0.25	2	0.03	2	8	0.5	8	8	16	4	1,024	8	0.25	170/38/3.1
821	2	16	0.06	2	8	0.25	16	16	16	4	512	4	0.5	170/66/50/3.1
830	1	2	0.06	1	8	0.25	4	8	32	4	512	16	0.25	170/50/3.1
Mode MICs for ESBL-negative:
K. pneumoniaeb	0.5	1	0.03	0.03	0.25	0.12	NDe	0.06	2	4	4	2	ND
E. coli K-12 J62-1 R− c	0.5	2	0.12	≤0.25	≤0.25	≤0.25	≤0.25	≤0.25	4	4	2	2	0.25
E. coli K-12 J62-1/803d	2	8	0.12	8	64	0.12	4	4	16	4	256	4	0.25	170

^aMICs are given in micrograms per milliliter. Abbreviations: Gm, gentamicin; Ak, amikacin; Cip, ciprofloxacin; Caz, ceftazidime; Caz-Clav, ceftazidime-clavulanate; Ctr, ceftriaxone; Ctx, cefotaxime; Cxm, cefuroxime; Fox, cefoxitin; Pip, piperacillin; Pip-Taz, piperacillin-tazobactam; Imp, imipenem. 

^bFrom reference 10. 

^cRecipient. 

^dTransconjugant of strain 803. 

^eND, not determined.