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. 2022 Apr 5;20:155. doi: 10.1186/s12967-022-03353-3

Table 1.

Characteristics of participants (Unweighted sample sizes and weighted %) according to cognitive impairment

Variables Cognitive impairment
(n = 1958/N = 11,422,175)
Non- Cognitive impairment
(n = 3409/N = 37,166,712)
P-value
Alcohol consumption
 Alcohol (gram/day), mean ± SE 4.62 ± 0.518 7.44 ± 0.413 < 0.001
 Non-drinkers 1659 (84.2) 2580 (73.1) < 0.001
 Drinkers 266 (14.2) 771 (25.1)
 Heavy drinkers 33 (01.6) 58 (01.9)
Demographic
 Age, years < 0.001
  70+ 1142 (66.0) 1498 (40.0)
  60–69 816 (34.0) 1911 (60.0)
 Gender 0.032
  Male 1079 (48.3) 1556 (43.6)
 Race < 0.001
  Others (including multi-racial) 68 (03.2) 230 (04.4)
  Other Hispanic 217 (09.3) 163 (02.4)
  Mexican American 413 (07.0) 340 (02.1)
  Non-Hispanic Black 548 (17.4) 488 (05.0)
  Non-Hispanic White 712 (63.2) 2188 (86.0)
 Education < 0.001
  Under 12th grade 1142 (48.9) 594 (13.1)
  High school graduate 412 (25.5) 864 (25.2)
  College or above 398 (25.5) 1950 (61.8)
 Marital status < 0.001
  Married/Living with partner 1003 (52.7) 2143 (68.8)
  Widowed/Divorced/Separated 808 (43.1) 1061 (27.9)
  Never married 90 (04.2) 134 (03.4)
 Income ratio < 0.001
  < 1 (Below poverty level) 490 (23.9) 297 (06.3)
  1–1.99 718 (40.1) 746 (20.2)
  2–3.99 366 (22.9) 1001 (32.7)
  4–5 (richest) 186 (13.2) 1058 (40.7)
Lifestyle
 Smoking 0.466
  Current smoker 281 (12.5) 381 (11.0)
  Former smoker 755 (39.8) 1375 (40.0)
  Non-smoker 919 (47.7) 1649 (49.0)
 Physical activity < 0.001
  Active 491 (32.7) 1365 (51.8)
  Inactive 839 (67.3) 1282 (48.2)
 BMI 0.155
  Underweight 36 (02.3) 38 (01.3)
  Normal 498 (28.0) 865 (25.9)
  Overweight 699 (35.8) 1266 (37.5)
  Obese 635 (33.9) 1183 (35.3)
 Attend social events < 0.001
  Difficulty 372 (21.3) 295 (07.3)
  No difficulty 1516 (78.7) 3075 (92.7)
 Comorbidities
  Diabetes mellitus 575 (28.0) 702 (18.0) < 0.001
  Hypertension 1220 (65.0) 1856 (51.7) < 0.001
  Stroke 207 (11.5) 149 (04.4) < 0.001
  CKD 428 (30.9) 397 (13.5) < 0.001

SE: Standard Error; BMI: Body Mass Index; CKD: Chronic Kidney Disease