Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Prevalence of BRCA1and BRCA2 mutations in ovarian cancer patients, by age of onset and family history.
| Number of cases | Number with a mutation | Proportion with a mutation (%) | |||||
|---|---|---|---|---|---|---|---|
| BRCA1 | BRCA2 | BRCA1/2 together | BRCA1 | BRCA2 | BRCA1/2 together | ||
| Age group | |||||||
| ≤ 50 | 31 | 3 | 1 | 4 | 9.7 | 3.2 | 12.9 |
| > 50 | 127 | 8 | 6 | 14 | 6.3 | 4.7 | 11.0 |
| Family history | |||||||
| Positive | 39 | 6 | 4 | 10 | 15.4 | 10.2 | 26.6 |
| Negative | 119 | 5 | 3 | 8 | 4.2 | 2.5 | 6.7 |
| All cases together | 158 | 11 | 7 | 18 | 7.0 | 4.4 | 11.4 |
