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Changes over time in the proportion of CD3+HLA-DR+ cells (A), CD8+CD38+HLA-DR+ cells (B) and CD8+CD38+ cells (C) in survivors; and changes over time in the proportion of CD3+HLA-DR+ cells (D), CD8+CD38+HLA-DR+ cells (E) and CD8+CD38+ cells (F) in non-survivors during the first week of hospitalization, Wilcoxon rank-sum test. **p < 0.01; ****p < 0.0001.
