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. 2022 Mar 14;13:861666. doi: 10.3389/fimmu.2022.861666

Table 2.

Characteristics of patients included in the study and the summary of the therapeutic approaches.

A (n=103) B (n=383) C (n=90) D (n=206) E (n=41)
Sex (male) 48 (46.7%) 206 (53.8%) 60 (66.7%) 115 (55.8%) 19 (46.3%)
Age (Mean ± SD) 63.62 ± 13.95 64.16 ± 14.53 61.16 ± 12.57 75.79 ± 11.36 64.05 ± 19.97
Chronic ischemic heart disease 34 (33.0%) 162 (42.3%) 23 (25.6%) 144 (69.9%) 19 (46.3%)
Hypertension 65 (63.1%) 270 (70.5%) 63 (70.0%) 179 (86.9%) 25 (61.0%)
Diabetes 29 (28.2%) 120 (31.3%) 34 (37.8) 88 (42.7%) 12 (29.3%)
Obesity 20 (19.4%) 140 (36.6%) 42 (46.7%) 63 (30.6%) 9 (22.0%)
Arrhythmia 15 (14.6%) 70 (18.3%) 6 (6.7%) 62 (30.1%) 14 (34.1%)
Bronchial asthma 12 (11.7%) 36 (9.4%) 4 (4.4%) 19 (9.2%) 2 (4.9%)
Chronic obstructive pulmonary disease 10 (9.7%) 44 (11.5%) 8 (8.9%) 33 (16.0%) 3 (7.3%)
Thyroid gland disease 8 (7.8%) 65 (17.0%) 13 (14.4%) 39 (18.9%) 6 (14.6%)
Chronic kidney disease 18 (17.5%) 59 (15.4%) 12 (13.3%) 73 (35.4%) 10 (24.4%)
Dyslipidemia 36 (35.0%) 141 (36.8%) 27 (30.0%) 84 (40.8%) 10 (24.4%)
Stroke history 9 (8.7%) 27 (7.0%) 9 (10.0%) 38 (18.4%) 5 (12.2%)
Cancer 15 (14.6%) 21 (5.5%) 5 (5.6%) 30 (14.6%) 10 (24.4%)
Hematological malignancy 2 (1.9%) 6 (1.6%) 2 (2.2%) 12 (5.8%) 1 (2.4%)
Interstitial lung disease 1 (0.97%) 6 (1.6%) 1 (1.1%) 7 (3.4%) 2 (4.9%)
Autoimmunity 7 (6.8%) 24 (6.3%) 6 (6.7%) 20 (9.7%) 3 (7.3%)
Immunodeficiency 1 (0.97%) 3 (0.78%) 5 (5.6%) 3 (1.5%) 0
Cirrhosis 0 0 0 4 (1.9%) 2 (4.9%)
Pregnancy 0 2 (0.52%) 3 (3.3%) 0 1 (2.4%)
Venous thromboembolism (during COVID-19) 7 (6.8%) 20 (5.2%) 5 (5.6%) 7 (3.4%) 0
Therapeutic approaches
Systemic corticosteroids 45 (43.7%) 344 (89.8%) 86 (95.6%) 177 (85.9%) 15 (36.6%)
Antivirals (remdesivir, favipiravir) 13 (12.6%) 146 (38.1%) 38 (42.2%) 70 (34.0%) 4 (9.8%)
Baricitinib 4 (3.9%) 28 (7.3%) 15 (16.7%) 16 (7.8%) 0
Tocilizumab 0 1 (0.3%) 4 (4.4%) 3 (1.5%) 0
Anakinra 0 1 (0.3%) 2 (2.2%) 0 0