Table 2.

Parameters in Baseline vs. Pregnancy-Specific Zone-MPC.

Design Element	Symbol	Baseline Value	Pregnancy Value	Effect of the Change
Zone-MPC
Day-time target glucose zone	GZL - GZH	90-120 mg/dL	80-110 mg/dL	Tighter glucose control as recommended for pregnant women with diabetes
Night-time target glucose zone	GZL - GZH	100-120 mg/dL	80-100 mg/dL	Tighter glucose control as recommended for pregnant women with diabetes
Reference fasting glucose	Gref	110 mg/dL	90 mg/dL	Controller deviation variables are calculated using a lower glucose value in the center of the zone
Active glucose velocity-penalty range	${\text{G}}_{\_}^v$ - ${\text{G}}_{+}^v$	140-180 mg/dL	120-180 mg/dL	Reduced post-prandial glucose exposure as recommended for pregnant women with diabetes
Meal bolus insulin decay curve	λ	4 hours	3 hours	Earlier relaxation of the insulin on board related constraint on controller action
Meal and Correction Control
Additional correction bolus threshold (added to the meal bolus)	τc	150 mg/dL	100 mg/dL	Reduced post-prandial glucose exposure with more assertive meal control strategy as recommended for pregnant women with diabetes
Target glucose in corrections	${\text{G}}_{\text{ref}}^{\text{corr}}$	150 mg/dL	90 mg/dL	More assertive hyperglycemia response integrated through correction bolus
Glucose threshold for reducing meal bolus	Gm	120 mg/dL	70 mg/dL	Reduced post-prandial glucose exposure as recommended for pregnant women with diabetes