Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Mar 22;13:883172. doi: 10.3389/fimmu.2022.883172

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Yuan, Chen, Wang, Xia, Huang, Zhou, Feng, Hu, Zhou and Ran

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

STAT3 was involved in the ADORA2A regulation of YKL-40 expression. (A) Immunofluorescence detection of astrocyte activation and STAT3 expression in the corpus callosum after CCH. (B) Western blot of the GFAP and STAT3 protein levels with the ADORA2A intervention. (C, D) Statistical analysis of the western blot results for GFAP and STAT3. (E, F) Western blot of the downstream YKL-40 protein level with ADORA2A and STAT3 intervention (E), and statistical analysis (F) of the western blot results. Scale bars = 20 μm; N = 5; N.S. indicated no significant difference, ***P < 0.001.