Table 1.
Details of the 16 prospective studies in this systematic review and meta-analysis
| Author | Year | Country | n | Mean patient age (years) | Age range (years) | ROBINS-I |
|---|---|---|---|---|---|---|
| Kelly | 2003 | USA | 420 | 54.3 | — | 2 |
| Mittendorf | 2005 | USA | 85 | 57.0 | 29–85 | 2 |
| Guillot | 2014 | France | 241 | 51.0 | 28–82 | 2 |
| Goyal | 2006 | UK | 367 | 58.0 | 49–81 | 2 |
| Moran | 2007 | ROI | 62 | — | 50–65 | 2 |
| Usmani | 2011 | Kuwait | 23 | 50.0 | 37–78 | 3 |
| Zetterlund | 2014 | Sweden | 1273 | 60.0 | 26–92 | 2 |
| D’Eredita | 2009 | Italy | 90 | 56.0 | 27–86 | 3 |
| Collado | 2010 | Spain | 65 | 51.9 | 38–69 | 3 |
| Klauber-DeMore | 2000 | USA | 76 | — | 3 | |
| Fancellu | 2012 | Italy | 140 | 56.0 | 26–89 | 2 |
| Intra | 2003 | Italy | 854 | — | — | 2 |
| Tunon-de-Lara | 2015 | France | 227 | — | 24–83 | 2 |
| van la Parra | 2008 | Netherlands | 51 | 59.0 | 39–81 | 3 |
| Leidenius | 2006 | Finland | 74 | 56.0 | 38–91 | 3 |
| Park | 2013 | ROK | 340 | 48.5 | 25–78 | 3 |
ROBINS-I, risk of bias in non-randomised studies of interventions; ROI, Republic of Ireland; ROK, Republic of Korea.