List of selected hits and their docking score with CK2.

S. no.	Compound ID	Compound	Source	Affinity (kcal mol−1)	pKi	LEa
1	5315739	N-Acetyldehydroanonaine	Zanthoxylum nitidum	−13.4	9.83	0.52
2	443716	Hydroxysanguinarine	Fumaria indica	−13.3	9.75	0.46
3	440583	Stylopine	Fumaria indica	−13.0	9.53	0.48
4	147329	Corysamine	Meconopsis aculeata	−12.6	9.24	0.45
5	2754650	Irenolone	Musa paradisiaca	−12.6	9.24	0.50
6	161899	Dehydroroemerine	Nelumbo nucifera	−12.5	9.17	0.52
7	6453733	l-N-Acetylanonaine	Zanthoxylum nitidum	−12.5	9.17	0.48
8	9817839	Dehydroevodiamines	Agrimonia pilosa	−12.5	9.17	0.48
9	146680	Elliptinone	Plumbago zeylanica	−12.3	9.02	0.40
10	633072	Chitranone	Plumbago zeylanica	−12.3	9.02	0.40
11	CX-4945	Silmitasertib	—	−10.2	7.48	0.36
12	SL-2052	Wortmannin	Penicillium funiculosum	−7.2	5.28	0.23

^aLE, ligand efficiency in values in kcal per mol per non-H atom.