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. 2022 Apr 5;27(4):253–e312. doi: 10.1093/oncolo/oyab078
Recombinant human endostatin
Generic/working name Recombinant human endostatin
Trade name Endostar
Company name Nanjing Simcere-Medgenn Bio-Pharmaceuticals Company
Drug type Biological
Drug class Angiogenesis-antivascular
Dose 15mg/m²
Route Continuous intravenous infusion
Schedule of administration Rh-endostatin (15mg/m2) was administered daily as a continuous intravenous pump infusion (7 continuous days) every 3 weeks.
Irinotecan
Generic/working name Irinotecan
Trade name Campto
Company name Pfizer Inc.
Drug type Biological
Drug class Topoisomerase I
Dose 60mg/m²
Route i.v.
Schedule of administration Irinotecan (60mg/m2) was administered intravenously on day 1 and day 8 every 3 weeks.
Cisplatin
Generic/working name Cisplatin
Trade name Nuoxin
Company name HANSOH PHARMA. Inc
Drug type Small molecule
Drug class Platinum compound
Dose 60mg/m²
Route i.v.
Schedule of administration Cisplatin (60mg/m2) was administered intravenously on day 1 every 3 weeks.