Fig. 4. Caspase-3 immune-expression in tumor sections of treated groups (caspase-3 antibody; ×100). (a) EAT, (b) 5e 2.5 mg kg−1, (c) 5e 5 mg kg−1, (d) 5d 2.5 mg kg−1 (d), (e) 5d 5 mg kg−1, (f) DOX, (g) % of caspase-3 immunoreactive area to total area through six fields per each section. The black arrow indicates caspase-3 expression within tumor cells. Data were presented as mean ± S.E.M of 5 fields. *Significant difference versus EAT (statistical analysis was performed by one-way ANOVA, followed by the Tukey's multiple comparison test; at p < 0.05).
