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. 2022 Feb 16;12(4):jkac041. doi: 10.1093/g3journal/jkac041

Table 1.

Summary of blood mQTLs identified in discovery and replication cohorts.

Cohorts Number of mQTL associations in total IBD genomic variants from de Lange et al. (2017; n = 241) CD-associated CpGs from Somineni et al. (2019; n = 1,189)
Discovery cohort (n = 238) Cis-associations
SNP-CpG associations 498,261 69 565
Unique SNPs 287,881 37 565
Unique CpGs 12,843 69 22
Trans-associations
SNP-CpG associations 37,187 1 0
Unique SNPs 27,664 1 0
Unique CpGs 1,118 1 0
Replication cohort (n = 780) Cis-associations
SNP-CpG associations 3,140,805 253 9,587
Unique SNPs 1,429,468 87 8,848
Unique CpGs 62,456 252 261
Trans-associations
SNP-CpG associations 175,588 4 184
Unique SNPs 106,900 4 85
Unique CpGs 7901 4 11