Table 1.
Cohorts | Number of mQTL associations in total | IBD genomic variants from de Lange et al. (2017; n = 241) | CD-associated CpGs from Somineni et al. (2019; n = 1,189) | |
---|---|---|---|---|
Discovery cohort (n = 238) | Cis-associations | |||
SNP-CpG associations | 498,261 | 69 | 565 | |
Unique SNPs | 287,881 | 37 | 565 | |
Unique CpGs | 12,843 | 69 | 22 | |
Trans-associations | ||||
SNP-CpG associations | 37,187 | 1 | 0 | |
Unique SNPs | 27,664 | 1 | 0 | |
Unique CpGs | 1,118 | 1 | 0 | |
Replication cohort (n = 780) | Cis-associations | |||
SNP-CpG associations | 3,140,805 | 253 | 9,587 | |
Unique SNPs | 1,429,468 | 87 | 8,848 | |
Unique CpGs | 62,456 | 252 | 261 | |
Trans-associations | ||||
SNP-CpG associations | 175,588 | 4 | 184 | |
Unique SNPs | 106,900 | 4 | 85 | |
Unique CpGs | 7901 | 4 | 11 |