Table 1.
UniProt | Protein names | AGI | SUBA/UniProt (∗) detected in extracellular space | Mutant phenotype | No. of gene models | High-impact mutations in 1001 genomes database |
---|---|---|---|---|---|---|
P22953 | HSP70-1 | AT5G02500 | Cytosol, nucleus∗ | A: altered plant growth and development (1), disabled immune response (2, 3), enhanced tolerance to heat shock, hypersensitive to ABA, compromised in the induced stomatal closure (2), γ-ray hypersensitivity and tolerance to salt, cadmium, and arsenic (4) B: did not reveal any difference in the resistance against pathogens Hyaloperonospora parasitica and Pseudomonas syringae pv tomato (3), more susceptible to P. syringae pv. Maculicola ΔhopI (5) |
2 | 1 (SNPs) |
Q9S7C0 | HSP70-14 | AT1G79930 | Cytosol, nucleus | B: indistinguishable from the wild type (6) | 2 | 4 (SNPs) |
Q9SAB1 | HSP70-16 | AT1G11660 | Cytosol, nucleus | B: failed flower opening, abnormal floral organ formation, impaired fertilization and seed setting (7), suppressed seed germination under cold stress conditions (8) | 4 | 1 (SNPs) |
P22954 | HSP70-2 | AT5G02490 | Cytosol, nucleus | B: did not reveal any difference in the resistance against pathogens Hyaloperonospora parasitica and Pseudomonas syringae pv tomato (3), more susceptible to P. syringae pv. Maculicola Δhop (5) | 1 | 0 |
O65719 | HSP70-3 | AT3G09440 | Cytosol, nucleus∗ | B: did not reveal any difference in the resistance against pathogens Hyaloperonospora parasitica and Pseudomonas syringae pv tomato (3) | 4 | 0 |
Q9LHA8 | HSP70-4 | AT3G12580 | Cytosol, nucleus | C: abnormal embryogenesis, defective seedlings with high levels of ROS–RNAi in an hsc70-1 mutant background (9) | 1 | 0 |
Q9S9N1 | HSP70-5 | AT1G16030 | Cytosol∗ | B: delayed growth under normal conditions, reduced survival of both seeds and seedlings after severe heat treatments, decreased growth activity under water deficit (10) | 1 | 0 |
Q9SKY8 | HSP70-8 | AT2G32120 | Cytosol | 2 | 11 (SNPs) | |
F4JMJ1 | HSP70-17 | AT4G16660 | Endoplasmic reticulum | 2 | 3 (SNPs) | |
Q9LKR3 | HSP70-11 (BIP1) | AT5G28540 | Endoplasmic reticulum, nucleus∗ | B: BIP1+BIP2 double mutation has an effect on the fusion of polar nuclei during female gametophyte development (11) | 1 | 0 |
Q39043 | HSP70-12 (BIP2) | AT5G42020 | endoplasmic reticulum, nucleus ∗ | B: compromised secretion of PR1 (12), enhanced fungal colonization (13), BIP1+ IP2 double mutation has an effect on the fusion of polar nuclei during female gametophyte development (11) | 3 | 0 |
Q8H1B3 | HSP70-13 (BIP3) | AT1G09080 | Endoplasmic reticulum, nucleus | B: BIP1+BIP2+BIP3 triple mutation is pollen lethal (14) | 2 | 5 (SNPs), 1 (INS), 1 (DEL) |
F4HQD4 | HSP70-15 | AT1G79920 | Golgi, cytosol, nucleus | B: severe growth retardation, impaired stomatal closure and accelerated wilting, enhanced tolerance to potyvirus infection (6) | 4 | 0 |
Q9LDZ0 | HSP70-10 | AT5G09590 | Mitochondrion∗ | 1 | 0 | |
Q8GUM2 | HSP70-9 | AT4G37910 | Mitochondrion, cytosol∗ | B: severe growth defects, abnormal mitochondria and alterations to respiration because of an inhibition of the cytochrome c oxidase (15) | 2 | 0 |
Q9C7X7 | HSP70-18 | AT1G56410 | Plastid, cytosol∗ | 1 | 10 (SNPs), 7 (INS), 46 (DEL) | |
Q9STW6 | HSP70-6 | AT4G24280 | Plastid∗ | B: variegated cotyledons, malformed leaves, growth retardation, impaired root growth (16), hsp70-6/hsp70-7 double mutants are lethal (17) | 1 | 0 |
Q9LTX9 | HSP70-7 | AT5G49910 | Plastid | B: hsp70-6/hsp70-7 double-mutants are lethal (17), defective protein import into chloroplasts during early developmental stages (18) | 1 | 1 (SNPs) |
Based on UniProt (Bateman et al., 2017), SUBA 4.0 (Hooper et al., 2017), the 1001 genome database (Weigel and Mott, 2009), and the previously reported response of HSP70 overexpression (A), loss-of-function mutation (B), and RNAi (C): 1, Sung and Guy (2003); 2, Clément et al. (2011); 3, Noël et al. (2007); 4, Cazalé et al. (2009); 5, Jelenska et al. (2010); 6, Jungkunz et al. (2011); 7, Chen et al. (2019); 8 Ashraf et al. (2021); 9, Lee et al. (2009); 10, Kozeko (2021); 11, Maruyama et al. (2010); 12, Wang et al. (2005); 13, Qiang et al. (2012); 14, Maruyama et al. (2014); 15, Wei et al. (2019); 16, Su and Li (2008); 17, Latijnhouwers et al. (2010); 18, Su and Li (2010). SNP, single nucleotide polymorphism; INS, insertion; DEL, deletion.