Figure 5.

(A) Sankey Plot of rhythm control treatment over time per group. Shown is the proportion of patients receiving antiarrhythmic drugs (AAD) and AF ablation (ablation) at each of the scheduled visits, split by randomized groups, and the proportion of patients changing from one type of therapy to the other. (B) Time to first AF ablation split by randomized group (Aalen–Johansen cumulative incidence curve). AF ablation was more often used in patients randomized to early therapy, with a steady increase in both randomized groups over time. At 2 years, 270/1395 (19.4%) patients randomized to early therapy had undergone AF ablation, while 97/1394 (7.0%) patients randomized to usual care had undergone ablation.