Figure 2. Neutralization of viral entry using pseudotyped VSVs.

Neutralization assays using VSVΔG pseudotyped with wild‐type SARS‐CoV‐2 spike protein. Panels show relative infectivity upon exposure to increasing concentrations of the indicated sybody constructs. Error bars correspond to standard deviation of three biological replicates.

1. Sb#15, Sb#68, or an equimolar mixture of both sybodies.
2. Sb#14, Sb#16, Sb#45, or, as a positive control, the previously described sybody MR3.
3. Neutralization by bivalent sybody‐Fc fusions.