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PAFE after 1.0 h of drug exposure time for concentrations ranging from 0.125 to 4.0 times the MIC for C. albicans OY31.5 and 90028
| Drug concn (multiple of MIC) | PAFE (h)
|
|||
|---|---|---|---|---|
| FLC | MK0991 | LY303366 | AMB | |
| C. albicans OY31.5 | ||||
| 0.125 | NTa | 0 | >12 | 2 |
| 0.25 | NT | 0 | >12 | 4 |
| 0.5 | NT | 0 | >12 | >12 |
| 1.0 | 0 | >12 | >12 | >12 |
| 2.0 | 0 | >12 | >12 | >12 |
| 4.0 | 0 | >12 | >12 | >12 |
| C. albicans 90028 | ||||
| 0.125 | NT | 0 | 0 | 2 |
| 0.25 | NT | 0 | >12 | >12 |
| 0.5 | NT | 0 | >12 | >12 |
| 1.0 | 0 | >12 | >12 | >12 |
| 2.0 | 0 | >12 | >12 | >12 |
| 4.0 | 0 | >12 | >12 | >12 |
NT, not tested.
