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. 2022 Mar 22;13:844199. doi: 10.3389/fphar.2022.844199

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Copyright © 2022 Abdul Rahman, Wan Ngah, Jamal, Makpol, Harun and Mokhtar.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Flow cytometry detection of apoptosis following annexin V-FITC/propidium iodide (PI) labelling. The lower left quadrant (Q3) contains viable cells, the lower right quadrant (Q4) contains early apoptotic cells, the upper right quadrant contains late apoptotic cells, and the upper left quadrant contains non-viable necrotic cells (Q1). A bar graph displaying the mean values from three independent experiments for (B) 1321N1, (C) SW1783, and (D) LN18. *p < 0.05 compare to control early or late apoptosis respectively, #p < 0.05 compare to EGCG early or late apoptosis respectively, $p < 0.05 compare to HC early or late apoptosis respectively.