TABLE 5.
Subnetwork enrichment analysis on gene dataset of p < 0.05, FDR.
| Expression target | 1321N1 No. of overlapping entities | 1321N1 p-value | LN18 No. of overlapping entities | LN18 p-value |
|---|---|---|---|---|
| MYC | 113 | 2.93E-17 | n/a | n/a |
| AKT1 | 137 | 2.35E-16 | 136 | 5.16E-10 |
| TGFB1 | 228 | 3.31E-13 | n/a | n/a |
| HIF1A | 117 | 1.98E-12 | 117 | 1.28E-07 |
| EGR1 | 77 | 4.94E-12 | n/a | n/a |
| JUN | 105 | 5.20E-12 | n/a | n/a |
| NFE2L2 | 72 | 7.90E-12 | 75 | 2.05E-09 |
| KLF4 | 53 | 9.72E-11 | n/a | n/a |
| MAP2K1 | 54 | 1.95E-10 | n/a | n/a |
| FGF2 | 107 | 3.23E-09 | n/a | n/a |
| ATF4 | 37 | 3.36E-09 | 37 | 3.96E-07 |
| PARP1 | 41 | 4.13E-09 | n/a | n/a |
| FOXM1 | 46 | 2.05E-08 | n/a | n/a |
| EIF2AK3 | 27 | 2.60E-08 | 25 | 1.19E-05 |
| NFYA | 26 | 3.20E-08 | n/a | n/a |
| EDN1 | 60 | 4.08E-08 | n/a | n/a |
| ATF3 | 32 | 4.44E-08 | n/a | n/a |
| VEGFA | 76 | 6.04E-08 | n/a | n/a |
| E2F4 | n/a | n/a | 27 | 1.04E-08 |
| MTOR | n/a | n/a | 88 | 1.24E-08 |
| E2F1 | n/a | n/a | 74 | 5.72E-08 |
| BRCA1 | n/a | n/a | 34 | 8.09E-08 |
| SRSF3 | n/a | n/a | 13 | 6.18E-07 |
| HSP90AA1 | n/a | n/a | 38 | 3.00E-06 |
| CUL4A | n/a | n/a | 11 | 8.03E-06 |
| VCP | n/a | n/a | 13 | 1.66E-05 |
| CAPN2 | n/a | n/a | 16 | 2.17E-05 |
| CDC20 | n/a | n/a | 12 | 2.93E-05 |
| CUL1 | n/a | n/a | 12 | 2.93E-05 |
| EGFR | n/a | n/a | 70 | 3.17E-05 |
| DDIT3 | n/a | n/a | 28 | 3.68E-05 |
| NRG1 | n/a | n/a | 40 | 4.68E-05 |
| SOD1 | n/a | n/a | 20 | 6.78E-05 |
| SREBF1 | n/a | n/a | 41 | 6.83E-05 |