TABLE 2.
Cox Regression Analysis for 1-Year SLKT Mortality
| Univariable |
Multivariable |
|||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P Value | aHR | 95% CI | P Value | |
| Kidney diagnosis | ||||||
| Unknown | — | — | — | |||
| AKI | 1.31 | 0.30-5.67 | 0.72 | |||
| CKD | 1.35 | 0.32-5.74 | 0.69 | |||
| Age per year | 1.01 | 1.00-1.03 | 0.10 | |||
| Female sex | 1.22 | 0.91-1.63 | 0.18 | |||
| Race | ||||||
| Caucasian | — | — | — | |||
| African American | 0.91 | 0.36-2.33 | 0.85 | |||
| Other | — | — | — | |||
| BMI per 1 kg/m2 | 0.95 | 0.90-1.00 | 0.07 | |||
| Year of SLKT per year | 0.88 | 0.82-0.95 | 0.001 | 0.85 | 0.78-0.92 | <0.001 |
| Hemodialysis at listing | 1.63 | 1.11-2.41 | 0.01 | 1.84 | 1.01-3.52 | 0.04 |
| Hemodialysis duration per day | 1.00 | 1.00-1.00 | 0.36 | |||
| eGFR <60 mL/minute/1.73 m2 per day | 1.00 | 0.99-1.00 | 0.11 | |||
| eGFR <25 mL/minute/1.73 m2 per day | 1.00 | 1.00-1.00 | 0.16 | |||
| Hepatitis C | 1.83 | 0.94-3.57 | 0.08 | |||
| EtOH related | 1.22 | 0.86-1.55 | 0.10 | |||
| NASH | 0.83 | 0.36-1.93 | 0.67 | |||
| Diabetes mellitus | 1.20 | 0.64-2.24 | 0.56 | |||
| Hypertension | 1.11 | 0.83-1.48 | 0.47 | |||
| Coronary artery disease | 0.84 | 0.41-1.72 | 0.63 | |||
| MELD at SLKT per point | 1.03 | 0.99-1.07 | 0.14 | |||
| Serum creatinine at SLKT per 1 mg/dL | 0.93 | 0.79-1.10 | 0.41 | |||
| Ascites | ||||||
| None | — | — | — | |||
| Mild | 0.26 | 0.02-3.58 | 0.31 | |||
| Moderate | 1.41 | 0.50-3.95 | 0.52 | |||
| Refractory | 2.23 | 0.71-7.07 | 0.17 | |||
| Hepatic encephalopathy | 0.71 | 0.40-1.28 | 0.26 | |||
| Hospitalization status | ||||||
| Home | — | — | — | |||
| Medical ward | 1.27 | 0.68-2.37 | 0.45 | |||
| Intensive care unit | 0.87 | 0.40-1.90 | 0.73 | |||
| Mechanical ventilation | 0.20 | 0.05-0.74 | 0.02 | |||
| Hemodialysis at SLKT | 0.77 | 0.56-1.06 | 0.11 | |||
| Cold ischemia time per minute | 1.00 | 1.00-1.00 | 0.57 | |||
| Warm ischemia time per minute | 1.00 | 0.99-1.01 | 0.51 | |||
| Deceased donor | 2.01 | 1.15-3.49 | 0.01 | |||
| Donor distance | ||||||
| Local | — | — | — | — | — | — |
| Regional | 1.28 | 0.44-3.74 | 0.65 | 1.04 | 0.31-3.49 | 0.96 |
| National | 6.60 | 3.41-12.73 | <0.001 | 4.76 | 1.78-12.74 | 0.002 |
| Delayed graft function | 3.26 | 1.26-8.46 | 0.02 | 3.14 | 1.61-6.12 | 0.001 |