TABLE 3.
Univariable |
Multivariable |
|||||
---|---|---|---|---|---|---|
HR | 95% CI | P Value | aHR | 95% CI | P Value | |
Kidney diagnosis | ||||||
Unknown | — | — | — | — | — | — |
AKI | 2.11 | 1.73-2.58 | <0.001 | 2.26 | 1.44-3.54 | <0.001 |
CKD | 1.64 | 1.12-2.41 | 0.01 | 1.63 | 0.97-2.74 | 0.07 |
Age per year | 1.01 | 1.00-1.03 | 0.10 | |||
Female sex | 1.05 | 0.81-1.37 | 0.71 | |||
Race | ||||||
Caucasian | — | — | — | |||
African American | 1.32 | 0.88-1.98 | 0.17 | |||
Other | 0.61 | 0.25-1.50 | 0.28 | |||
BMI per 1 kg/m2 | 1.00 | 1.00-1.00 | 0.16 | 1.00 | 1.00-1.01 | <0.001 |
Year of admission | ||||||
2002-2006 | — | — | — | |||
2007-2010 | 1.42 | 1.01-1.98 | 0.04 | |||
2011-2014 | 1.48 | 0.44-4.95 | 0.53 | |||
2015-2017 | 1.06 | 0.33-3.42 | 0.92 | |||
Hemodialysis at listing | 1.09 | 0.80-1.47 | 0.59 | |||
Hemodialysis duration per day | 1.00 | 1.00-1.00 | 0.52 | |||
eGFR <60 mL/minute/1.73 m2 per day | 1.00 | 0.99-1.00 | 0.40 | |||
eGFR <25 mL/minute/1.73 m2 per day | 1.00 | 1.00-1.00 | 0.27 | |||
Hepatitis C | 1.19 | 0.82-1.74 | 0.37 | |||
EtOH related | 1.06 | 0.80-1.41 | 0.70 | |||
NASH | 1.27 | 0.88-1.83 | 0.20 | |||
Diabetes mellitus | 1.36 | 1.08-1.71 | 0.008 | |||
Hypertension | 1.32 | 0.98-1.76 | 0.07 | |||
Coronary artery disease | 1.33 | 0.97-1.83 | 0.08 | |||
MELD at SLKT per point | 1.00 | 0.99-1.02 | 0.45 | |||
Serum creatinine at SLKT per 1 mg/dL | 0.89 | 0.83-0.96 | 0.002 | 0.90 | 0.82-0.98 | 0.02 |
Ascites | ||||||
None | — | — | — | |||
Mild | 0.73 | 0.49-1.10 | 0.13 | |||
Moderate | 1.01 | 0.73-1.41 | 0.93 | |||
Refractory | 1.17 | 0.82-1.66 | 0.39 | |||
Hepatic encephalopathy | 1.10 | 0.87-1.39 | 0.41 | |||
Hospitalization status | ||||||
Home | — | — | — | |||
Medical ward | 1.20 | 0.70-2.06 | 0.51 | |||
Intensive care unit | 1.31 | 0.84-2.03 | 0.23 | |||
Mechanical ventilation | 1.70 | 1.14-2.53 | 0.009 | 1.95 | 1.59-2.38 | <0.001 |
Hemodialysis at SLKT | 0.77 | 0.56-1.06 | 0.11 | |||
Cold ischemia time per minute | 1.00 | 1.00-1.00 | 0.37 | |||
Warm ischemia time per minute | 1.01 | 1.00-1.01 | 0.02 | 1.01 | 1.00-1.01 | 0.01 |
Donor distance | ||||||
Local | — | — | — | — | — | — |
Regional | 0.96 | 0.67-1.39 | 0.85 | 1.39 | 1.01-1.91 | 0.04 |
National | 2.67 | 1.52-4.69 | 0.001 | 3.48 | 2.09-5.78 | <0.001 |
Delayed graft function | 1.22 | 0.81-1.82 | 0.34 |