Skip to main content
. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: Liver Transpl. 2021 Aug 20;27(11):1613–1622. doi: 10.1002/lt.26232

TABLE 3.

Cox Regression Analysis for Overall SLKT Mortality

Univariable
Multivariable
HR 95% CI P Value aHR 95% CI P Value
Kidney diagnosis
 Unknown
 AKI 2.11 1.73-2.58 <0.001 2.26 1.44-3.54 <0.001
 CKD 1.64 1.12-2.41 0.01 1.63 0.97-2.74 0.07
Age per year 1.01 1.00-1.03 0.10
Female sex 1.05 0.81-1.37 0.71
Race
 Caucasian
 African American 1.32 0.88-1.98 0.17
 Other 0.61 0.25-1.50 0.28
BMI per 1 kg/m2 1.00 1.00-1.00 0.16 1.00 1.00-1.01 <0.001
Year of admission
 2002-2006
 2007-2010 1.42 1.01-1.98 0.04
 2011-2014 1.48 0.44-4.95 0.53
 2015-2017 1.06 0.33-3.42 0.92
Hemodialysis at listing 1.09 0.80-1.47 0.59
Hemodialysis duration per day 1.00 1.00-1.00 0.52
eGFR <60 mL/minute/1.73 m2 per day 1.00 0.99-1.00 0.40
eGFR <25 mL/minute/1.73 m2 per day 1.00 1.00-1.00 0.27
Hepatitis C 1.19 0.82-1.74 0.37
EtOH related 1.06 0.80-1.41 0.70
NASH 1.27 0.88-1.83 0.20
Diabetes mellitus 1.36 1.08-1.71 0.008
Hypertension 1.32 0.98-1.76 0.07
Coronary artery disease 1.33 0.97-1.83 0.08
MELD at SLKT per point 1.00 0.99-1.02 0.45
Serum creatinine at SLKT per 1 mg/dL 0.89 0.83-0.96 0.002 0.90 0.82-0.98 0.02
Ascites
 None
 Mild 0.73 0.49-1.10 0.13
 Moderate 1.01 0.73-1.41 0.93
 Refractory 1.17 0.82-1.66 0.39
Hepatic encephalopathy 1.10 0.87-1.39 0.41
Hospitalization status
 Home
 Medical ward 1.20 0.70-2.06 0.51
 Intensive care unit 1.31 0.84-2.03 0.23
Mechanical ventilation 1.70 1.14-2.53 0.009 1.95 1.59-2.38 <0.001
Hemodialysis at SLKT 0.77 0.56-1.06 0.11
Cold ischemia time per minute 1.00 1.00-1.00 0.37
Warm ischemia time per minute 1.01 1.00-1.01 0.02 1.01 1.00-1.01 0.01
Donor distance
 Local
 Regional 0.96 0.67-1.39 0.85 1.39 1.01-1.91 0.04
 National 2.67 1.52-4.69 0.001 3.48 2.09-5.78 <0.001
Delayed graft function 1.22 0.81-1.82 0.34