Table 3.
Dose Effects Predicting Epigenetic Age Acceleration from Marijuana Use among users only
| Epigenetic Age Measure | ||
|---|---|---|
| DNAmGrimAge | DunedinPoAm | |
| β | β | |
| Blood Cell Counts | ||
| Naïve CD8+ T cells | −.20* | −.14 |
| CD8+ CD28- CD45 RA- T cells | .14 | .23** |
| Plasmablasts | −.11 | .20* |
| Naïve CD4+ T cells | .18* | .14 |
| Natural Killer cells | .02 | .05 |
| Monocytes | −.03 | −.14* |
| Granulocytes | .33** | .15 |
| Chronological Age | .39*** | .03 |
| Demographic Characteristics | ||
| Gender (Male = 1, Female = 2) | −.06 | .16* |
| Racial/Ethnic Minority Membership | .32*** | .48*** |
| Family of Origin Income | −.10 | −.08 |
| Lifetime Cigarette Use | .19** | .22*** |
| Lifetime Marijuana Use | .29*** | .29*** |
Note.
***
p < .001.
**
p < .01.
*
p < .05.
β weights are from the full model. N = 113