Table 3.
Logistic regression analyses for factors associated with modified Rankin Scale scores of 0–2 at year-1 after ICU discharge
| Variables | Univariate analysis | Multivariable analysis | ||
|---|---|---|---|---|
| OR [95% CI] | p-value | OR [95% CI] | p-value | |
| Age, per year | 0.93 [0.89–0.97] | 0.0006 | 0.92 [0.88–0.97] | 0.01 |
| GCS at ICU admission, per point | 1.13 [0.97–1.33] | 0.12 | ||
| Focalization sign at ICU admission | 1.93 [0.58–6.39] | 0.27 | ||
| Seizures | 1.46 [0.45–4.69] | 0.52 | ||
| Status epilepticus | 0.84 [0.21–3.36] | 0.81 | ||
| SOFA at day 1, per point | 0.88 [0.75–1.03] | 0.1 | ||
| Maximal temperature at ICU admission, per degree | 1.09 [0.65–1.82] | 0.74 | ||
| Underlying immunosuppression | 0.19 [0.05–0.79] | 0.019 | 0.26 [0.04–1.59] | 0.13 |
| CSF elements, per element | 1.00 [0.99–1.00] | 0.40 | ||
| CSF protein level, per g/L | 0.65 [0.39–1.09] | 0.09 | ||
| Invasive mechanical ventilation | 0.22 [0.05–1.04] | 0.05 | 0.09 [0.01–0.84] | 0.03 |
| Renal replacement therapy | 0.83 [0.23–2.99] | 0.78 | ||
| Vasopressors | 0.35 [0.10–1.22] | 0.09 | ||
| Vasculitis on brain MRI | 0.44 [0.076–2.576] | 0.35 | ||
| Time from the onset of neurological symptoms to acyclovir, days | 0.99 [0.91–1.08] | 0.74 | ||
| High dose of steroids | 0.71 [0.06–8.87] | 0.78 | ||
CSF, cerebrospinal fluid; GCS, Glasgow Coma Scale; ICU, intensive care unit; MRI, magnetic resonance imaging; SOFA, Sequential Organ Failure Assessment