Table 1. Enzymatic Inhibitory Activity of S-217622 against Human Host Proteases and an HIV-1 Protease^a.

protease	IC50 (μM)
caspase 2	>100
chymotrypsin	>100
chathepsin B	>100
chathepsin D	>100
chathepsin G	>100
chathepsin L	>100
thorombin	>100
HIV-1 protease	>100

^aInhibitory activities were <50% at 100 μM.