Effect of anti-IL-6 mAb treatment on post-burn body weight and composition. A, Change in total body weight in post-burn mice treated with vehicle or anti-mouse IL-6R monoclonal antibody daily (anti-IL-6 mAb) daily for 7 days. B, Adipose tissue weights expressed as a percentage of body weight demonstrating alterations in inguinal WAT (iWAT) and epidydimal WAT (eWAT). C, Increased dietary intake as a percentage of total food consumed in anti-IL-6-treated burn mice compared with controls and untreated burn mice. D, Increased circulating levels of serum amyloid A (SAA) in untreated burn mice relative to control and anti-IL-6-treated burn mice. Values are presented as mean ±standard error. *P < .05; **P < .01; ***P < .001; ****P < .0001, n = 7/group