Table 2.

Oritavancin Mean (CV%) Plasma Pharmacokinetic Parameters (1200-mg Infusions)

Parameter	Current Formulation	New Formulation
Dose (mg)	1200	1200
IV Infusion Duration	3 hours	1 hour
n	50	50
C max (µg/mL)	112 (30.8)	148 (29)
T max (hour)a	3.29 (3.02–5.83)	1.15 (0.90–3.17)
AUC0-72 (µg * h/mL)	1470 (39.7)	1460 (35.1)
AUC0-168 (µg * h/mL)	1760 (41.4)	1750 (35.0)

Abbreviations: AUC, area under the concentration-time curve; CV, coefficient of variation; IV, intravenous.

Median (minimum-maximum).