Table 3.

Relative AUC Exposure Evaluation of Current vs New Formulations of Oritavancin

AUC Parameter	Least Squares Geometric Mean		Ratio (%) of Geometric Means (Test/Reference)	90% CI of the Ratio (Test/Reference)
	Reference	Test
AUC0-72 (µg * h/mL)	1290 (n = 44)	1410 (n = 43)	110	95.0–126
AUC0-168 (µg * h/mL)	1580 (n = 42)	1680 (n = 42)	107	92.3–123

Abbreviations: AUC, area under the concentration-time curve; CI, confidence interval.

NOTE: Reference: Current formulation of oritavancin. Test: New formulation of oritavancin.