Table 2. Oxidative stress markers in study subjects.
Characteristic of study subjects | Group 1 | Group 2 | Group 3 | p |
---|---|---|---|---|
eGFR > 89 mL/min/1.73 m2 (n = 121) | eGFR 60–89 mL/min/1.73 m2 (n = 74) | eGFR < 60 mL/min/1.73 m2 (n = 32) | ||
Mean ± SE | ||||
H2O2 (μmol/mg creatinine) | 89.99 ± 27.12 | 45.73 ± 11.66 | 32.83 ± 4.09 | 0.003 a * |
8-iso-PGF2α (pg/mg creatinine) | 13,342.32 ± 2,346.87 | 47,356.27 ± 31,982.64 | 13,172.56 ± 3,335.76 | 0.883a |
OxLDL/β2GPI complex (units/mL) | 0.48 ± 0.03 | 0.54 ± 0.05 | 0.63 ± 0.08 | 0.121a |
Abbreviations: eGFR, estimated glomerular filtration rate; 8-iso-PGF2α, 8-isoprostaglandin F2α; oxLDL/β2GPI complex, oxidized low-density lipoprotein/beta-2-glycoprotein-I.
Data were expressed in n (%), mean ± SEM.
Notes: p = significance (*p < 0.05 is considered statistically significant); SEM = standard error mean; a = Kruskal–Wallis H tests.