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. 2022 Apr 5;17(4):e0263113. doi: 10.1371/journal.pone.0263113

Table 2. Oxidative stress markers in study subjects.

Characteristic of study subjects Group 1 Group 2 Group 3 p
eGFR > 89 mL/min/1.73 m2 (n = 121) eGFR 60–89 mL/min/1.73 m2 (n = 74) eGFR < 60 mL/min/1.73 m2 (n = 32)
Mean ± SE
H2O2 (μmol/mg creatinine) 89.99 ± 27.12 45.73 ± 11.66 32.83 ± 4.09 0.003 a *
8-iso-PGF2α (pg/mg creatinine) 13,342.32 ± 2,346.87 47,356.27 ± 31,982.64 13,172.56 ± 3,335.76 0.883a
OxLDL/β2GPI complex (units/mL) 0.48 ± 0.03 0.54 ± 0.05 0.63 ± 0.08 0.121a

Abbreviations: eGFR, estimated glomerular filtration rate; 8-iso-PGF2α, 8-isoprostaglandin F2α; oxLDL/β2GPI complex, oxidized low-density lipoprotein/beta-2-glycoprotein-I.

Data were expressed in n (%), mean ± SEM.

Notes: p = significance (*p < 0.05 is considered statistically significant); SEM = standard error mean; a = Kruskal–Wallis H tests.