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. 2022 Apr 5;17(4):e0263113. doi: 10.1371/journal.pone.0263113

Table 3. Factors affecting the eGFR level in T2DM patients (n = 189).

Dependent variable Adjusted R square Predictor Standardized Coefficients β p-value
eGFR (mL/min/1.73 m2) 0.182
H2O2 (μmol/mg Cre) 0.157 0.036*
8-iso-PGF2α (pg/mg creatinine) 0.018 0.791
OxLDL/β2GPI complex (units/mL) -0.109 0.119
UACR (mcg/mg Cre) -0.061 0.402
HbA1c (%) 0.113 0.098
Systole (mmHg) -0.247 0.011*
Diastole (mmHg) 0.201 0.035*
Age (years) -0.268 <0.001**
Gender (female) 0.191 0.005*
BMI (kg/m2) 0.057 0.404

Abbreviations: CI, confidence interval; eGFR, estimated glomerular filtration rate; UACR, urine albumin to creatinine ratio; H2O2, hydrogen peroxide; 8-iso-PGF2α, 8-isoprostaglandin F2α; OxLDL/β2GPI complex, oxidized low-density lipoprotein/beta-2-glycoprotein-I; HbA1c, hemoglobin A1c; BMI, body mass index;

*statistically significant (p<0.05);

**statistically significant (p<0.001).