Table 3. Factors affecting the eGFR level in T2DM patients (n = 189).
Dependent variable | Adjusted R square | Predictor | Standardized Coefficients β | p-value |
---|---|---|---|---|
eGFR (mL/min/1.73 m2) | 0.182 | |||
H2O2 (μmol/mg Cre) | 0.157 | 0.036* | ||
8-iso-PGF2α (pg/mg creatinine) | 0.018 | 0.791 | ||
OxLDL/β2GPI complex (units/mL) | -0.109 | 0.119 | ||
UACR (mcg/mg Cre) | -0.061 | 0.402 | ||
HbA1c (%) | 0.113 | 0.098 | ||
Systole (mmHg) | -0.247 | 0.011* | ||
Diastole (mmHg) | 0.201 | 0.035* | ||
Age (years) | -0.268 | <0.001** | ||
Gender (female) | 0.191 | 0.005* | ||
BMI (kg/m2) | 0.057 | 0.404 |
Abbreviations: CI, confidence interval; eGFR, estimated glomerular filtration rate; UACR, urine albumin to creatinine ratio; H2O2, hydrogen peroxide; 8-iso-PGF2α, 8-isoprostaglandin F2α; OxLDL/β2GPI complex, oxidized low-density lipoprotein/beta-2-glycoprotein-I; HbA1c, hemoglobin A1c; BMI, body mass index;
*statistically significant (p<0.05);
**statistically significant (p<0.001).