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. 2021 Dec 29;207(2):208–217. doi: 10.1093/cei/uxab038

Table 2.

Reference range of percentages of T lymphocyte subsets in different age groups

Parameters All (18–44) years (45–65) years >65years
n = 309 n = 101 n = 106 n = 102
Age Mean±SD 50.52 ± 18.00 30.73 ± 6.52 54.63 ± 6.37 73.59 ± 6.60
Sex Male:female 171:138 56:45 56:50 59:43
CD3+%lymphocyte cells Median 67.90% 68.5% 66.55% 64.2%
Reference range Cl 90% (49.58–79%) (55.33–79.28%) (50.06–78.53%) (48.52%–81.26%)
CD3+CD4+%CD3+ Median 52.8% 50.4% 53.95% 57.05%
Reference range Cl 90% (37%–68.34) (34.6–65.46%) (41.85%–69.49%) (35.43%–71.17%)
CD3+CD4+%lymphocyte cells Median 34.1% 32.35% 35.05% 35.1%
Reference range Cl 90% (23.86–47.86%) (23.7–45.81%) (25.64–48.49%) (19.36–50.13%)
CD4+Tn%CD3+CD4+ Median 4.3% 6% 3.45% 2.6%
Reference range Cl 90% (1–10.82%) (2.14–11.62%) (1.1–11.16%) (0.52–7.09%)
CD4+Tscm%CD3+CD4+ Median 17.6 26.35 13.55 11.4
Reference range Cl 90% (3.3–38.94%) (8.34–41.30%) (3.3–35.77%) (2.02–30.55%)
CD4+Tcm%CD3+CD4+ Median 27.00% 26.1% 28.1% 26.45%
Reference range Cl 90% (14.7–43.42%) (11.41–38.13%) (16.37–43.20%) (14.81–52.9%)
CD4+Tem%CD3+CD4+ Median 20.3% 17.6% 22.1% 20.85%
Reference range Cl 90% (10.48–40.2%) (8.03–34.67%) (10.88–42.27%) (10.27–42.41)
CD4+Tte%CD3+CD4+ Median 0.4% 0.5% 0.4% 0.7%
Reference range Cl 90% (0.01–9.06%) (0.01–10.24%) (0.01–8.58%) (0.01–10.7%)
CD3+CD8+%CD3+ Median 36.8% 38% 35.3% 34.8%
Reference range Cl 90% (23–51.44%) (25.13–53.70%) (22.98–48.7%) (18.25–57.71%)
CD3+CD8+%Lymphocyte cells Median 24.9% 26.15% 22.85% 20.85%
Reference range Cl 90% (13.1–37.42%) (16.56–40.02%) (13.38–35.17%) (10.39–37.97%)
CD8+Tn%CD3+CD8+ Median 3.2% 6.45% 2.5% 0.8%
Reference range Cl 90% (0.3–9.34%) (2.05–10.33%) (0.5–8.02%) (0.11–4.75%)
CD8+Tscm%CD3+CD8+ Median 13.7% 28.05% 11.6% 6.1%
Reference range Cl 90% (1.9–38.42%) (8.30–48.90%) (2.67–31.81%) (1.3–21.86%)
CD8+Tcm%CD3+CD8+ Median 8.9% 7.4% 8.8% 12.15%
Reference range Cl 90% (3.38–21.04%) (2.73–15.05%) (3.41–21.46%) (4.91–27.45%)
CD8+Tem%CD3+CD8+ Median 22.8% 22.3% 21.35% 27.45%
Reference range Cl 90% (6–48.8%) (5.49–37.72%) (6.94–49.84%) (4.91–27.45%)
CD8+Tte%CD3+CD8+ Median 12.2% 10.5% 13.85% 10.6%
Reference range Cl 90% (1.9–38.42%) (2.00–30.62%) (1.77–39.05%) (1.47–45.85%)